Flow Cytometry
Flow cytometry provides a versatile platform for assessing pharmacodynamic (PD) responses in clinical trials. Using high-parameter single-cell analysis, flow cytometry can identify granular changes in cell biology and function in response to a therapeutic. Performing this analysis early in clinical trials can help determine whether a therapeutic engages its target, identify potential safety and tolerability issues, and ascertain an optimal dosage range.
Expertise With Flow Cytometry:
Sample Analysis
We offer both real-time and batch sample analysis, ensuring every cell population can be assessed during crucial early-phase clinical studies through the approach that best suits your needs.
Client-First Focus
Timelines, regulatory requirements, and intended use of data are considered from the outset of a study.
State-of-the-art Facililty
Our premier suite of flow cytometers gives us the capability to leverage the ideal platform for your assay.
360biolabs Assay Solutions
Flow Cytometry
Flow cytometry can contribute to evaluating PD output through:
- Receptor occupancy and target engagement
- Biomarker expression analysis
- Immunophenotyping
- Cell enumeration
- Cellular target identification
- Cytokine and signaling pathway analysis
- Cell cycle analysis
- Apoptosis and cell death assessment
- Functional assays (cytotoxicity, phagocytosis and other effector functions)
- Minimal residual disease detection
- Dose-response studies
- Ex-vivo stimulation
Learn more about our comprehensive services:
Related Content
Blog: Flow Cytometry
Read our latest blog on Flow Cytometry in Clinical Trials: A Powerful and Versatile Tool.
Quality
Our method development and validation procedures align with global scientific regulatory frameworks such as FDA, EMEA, and ICH.
Australian Locations
Our purpose-built facilities in Melbourne and Brisbane are situated in medical research precincts, allowing assaying time-sensitive samples.